2021-9-22  wednesday

  Fine chemicals...
Add:No.350-7,Middle Xingang Road,Haizhu District,Guangzhou City,Guangdong Province,P.R.China
【Product Name】10-Hydroxycamptothecin
【Category】 Fine chemicals > Fine chemicals



Production name: 10-Hydroxycamptothecin

Molecular formula: C20H16N2O5

Molucular weight:364.36

Formulation: light yellow white crystalline powder

Purity: 98%

10-hydroxycamptothecin is the derivative of camptothecine that is a micro-alkaloid from camptotheca Acuminate (a tree native to mainland China). is a kind of pharmaceutical intermediate, an alkaloid originally isolated from the Camptotheca acuminata, exerted inhibitory effects on DNA topoisomerase (Topo )[1]and has anticancer activity in vitro and in vivo. It can also induce differentiation of leukemia MELC[2]and HL-60[3]cells. The purpose of this study is to investigate the proliferation-inhibiting and differentiation-inducing actions of HCPT on human hepatoma Hep G2 cells.

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